antisense oligonucleotide meaning in English
反义寡核苷酸
Examples
- Effects of antisense oligonucleotide on expression of tissue factor in culturec human umbilical vein endothelial cells injured by anoxia - reoxygention
反义寡脱氧核苷酸对内皮细胞缺氧再复氧损伤组织因子表达的影响 - Co - culture of sperm with endometrial cells treated with antisense oligonucleotide against cftr , or with bicarbonate secretion - defective cf epithelial cells , resulted in lower sperm capacitation and egg - fertilizing ability
相反,如果用缺乏cftr的细胞,或者是cftr发生突变的细胞,精子便不能有效获能。 - It was proved that tle1 expression was up - regulated in cervix cancer , while aes expression was up - regulated in gastric cancer . antisense oligonucleotide or small interfering rna specific against aes or tle1 could inhibit the expression of corresponding molecule
设计、合成针对这两种分子的反义核酸和小分子于扰rna ( sirna ) ,转染宫颈癌细胞系hela和胃癌细胞系sgc7901 ,发现反义核酸和sirna均可抑制相亡分子的表达, sinya的抑制作日更为明显。